Poly(hexamethylenebiguanide)hydrochloride PHMB

get together have shrink guanidine, get together ammoniac propyl metformin (PAPB), Poly real (iminocarbonimidoyliminocarbonimidoylimino - 1, 6 - hexanediyl) hydrochloride

1. Basic information
Chemical formula: (C8H17N5)n·xHCl
CAS login number: 32289-58-0 (USA); [27083-27-8] (Europe); [133029-32-9] (INCI)
EC Code: [608-723-9]/[608-042-7]
Molecular formula: (C8H17N5)n·xHCL, n=12~16
Other names: get together have shrink guanidine, get together ammoniac propyl metformin (PAPB), Poly real (iminocarbonimidoyliminocarbonimidoylimino - 1, 6 - hexanediyl) hydrochloride
Appearance: Pure product is white powder, 20% solid content aqueous solution is colorless liquid

2, physical and chemical properties
PH value: The PH value of pure 1% aqueous solution is 6.58.5, and the PH value of aqueous solution with 20% solid content is 4.06.0
Solubility: easily soluble in water, aqueous solution colorless and odorless
Stability: The active ingredient is thermally stable and non-volatile
Corrosion: It is basically non-corrosive to stainless steel, copper, carbon steel and other metals and wood and plastics

3, antibacterial performance
Polyhexamethylenebiguanide hydrochloride is a kind of antibacterial polymer containing guanidine group in main chain, which has excellent antibacterial properties. Its antibacterial mechanism mainly includes:

The collapse of the cell membrane structure, the formation of transmembrane pores, resulting in the rupture of the cell membrane, the destruction of microbial energy metabolism, and the loss of bacterial virus activity.
Guanidine has high activity, the polymer is positive, and all kinds of bacteria and viruses are generally negative, so guanidine salt is easy to be adsorbed, so that bacteria and viruses can not divide and multiply, and lose activity.
Polyhexamethylene-biguanide hydrochloride can kill gram-positive bacteria, gram-negative bacteria, fungi and yeast, etc. Compared with polyhexamethylene-biguanide, the antibacterial effect of polyhexamethylene-biguanide on Bacillus glutarum, brewer's yeast and Aspergillus Niger is better than that of polyhexamethylene-biguanide. In addition, it also has a bactericidal effect on many spores.

4. Application field
In the field of medicine: For the preparation of antibacterial drugs and disinfectants and other medical products, such as contact lenses, eye drops and surgical disinfection. At the same time, gauze or dressing containing 0.2% polyhexamethylene biguanide antibacterial component can be used for surgical wounds and wound dressing to prevent bacterial infection and growth.
Personal care products: can be used in skin care products, washing supplies, disposable wet wipes, wet towels, napkins, antibacterial hand sanitizer and other products, with antibacterial and mildew prevention effect.
Sanitary antiseptic field: Used for disinfection of swimming pools, with non-irritating characteristics, but also to enhance the activity of water, reduce ammonia and phosphate in water, control algae growth.
Aquaculture: Adding polyhexamethylene biguanide hydrochloride to aquatic water system can inhibit bacteria in water system and prevent aquatic diseases caused by bacteria.
Textile field: It can be used for antibacterial finishing of textiles, because of its good heat stability, it can be added to the melt spinning solution to make antibacterial synthetic fiber. At the same time, it can also be used in antibacterial laundry liquid, no irritation to the skin, washed clothing is not harmful to the human body.
5. Security
Polyhexamethylene-guanidine hydrochloride has low toxicity and can be used for a long time. However, in order to ensure safety and prevent environmental pollution, users need to comply with relevant regulations in the use and handling process, and pay attention to avoid the occurrence of adverse conditions such as allergies and ingestion.

In summary, polyhexamethylene-biguanide hydrochloride is a kind of chemical substance with broad-spectrum antibacterial properties, easy to dissolve in water, good stability and low toxicity, which has been widely used in many fields such as medicine, personal care, health anticorrosion, aquaculture and textile.